Abstract
OBJECTIVE: To separate the total extract of Ephedra sinica Stapf into two parts, ephedrine alkaloids and non-ephedrine alkaloids, and to investigate if the non-ephedrine alkaloids part has thrombolysis effect. METHODS: Chloroform was used to isolate ephedrine alkaloids and non-ephedrine alkaloids. A cerebral ischemic model of SD mice developed by ferric chloride was applied to test the thrombolysis effect of non-ephedrine alkaloids part. RESULTS: The non-ephedrine alkaloids part had apparent thrombolysis effect. CONCLUSION: There may be some effective components in non-ephedrine alkaloids part which has shown the total pharmacological effect of Ephedra sinica Stapf.
| Original language | English |
|---|---|
| Pages (from-to) | 423-425 |
| Number of pages | 3 |
| Journal | Chinese Pharmaceutical Journal |
| Volume | 39 |
| Issue number | 6 |
| Publication status | Published - Jun 2004 |
Scopus Subject Areas
- Pharmacology
- Pharmaceutical Science
User-Defined Keywords
- Cerebral ischemic model
- Ephedra sinica Stapf
- Non-ephedrine alkaloids
- Thrombolysis