Separation and preconcentration of persistent organic pollutants by cloud point extraction

Shunping Xie, Man Chin Paau, Cheuk Fai Li, Dan Xiao*, Martin M F CHOI

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

99 Citations (Scopus)


Persistent organic pollutants (POPs) are recognized as a class of poisonous compounds which pose risks of causing adverse effects to human health and the environment. Thus, it is very important to detect POPs in environmental and biological samples. The identification and determination of very low levels of POPs in complex matrices is extremely difficult. Recently a promising environmentally benign extraction and preconcentration methodology based on cloud point extraction (CPE) has emerged as an efficient sample pretreatment technique for the determination of trace/ultra-trace POPs in complex matrices. The purpose of this paper is to review the past and latest use of CPE for preconcentrating POPs and its coupling to different contemporary instrumental methods of analysis. First, the comparison of various extraction techniques for POPs is described. Next, the general concept, influence factors and other methods associated with CPE technique are outlined and described. Last, the hyphenations of CPE to various instrumental methods for their determination are summarized and discussed.

Original languageEnglish
Pages (from-to)2306-2317
Number of pages12
JournalJournal of Chromatography A
Issue number16
Publication statusPublished - Apr 2010

Scopus Subject Areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

User-Defined Keywords

  • Cloud point extraction
  • Detection
  • Persistent organic pollutants
  • Preconcentration


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