Abstract
A rapid and convenient detection method for biogenic polyamines is of great importance for early diagnosis of many diseases. In this work, a tetraphenyl ethylene (TPE) conjugated pentiptycene has been synthesized and showed to be a highly responsive fluorescent sensor toward polyamines. The detection limit of this probe is in the sub-micromolar level, and it also shows good selectivity for spermine. This small organic molecular bio-indicator can be used to detect spermine in artificial urine, demonstrating the potential application in clinical practice.
Original language | English |
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Article number | 117856 |
Journal | Journal of Luminescence |
Volume | 232 |
Early online date | 17 Dec 2020 |
DOIs | |
Publication status | Published - Apr 2021 |
Scopus Subject Areas
- Biophysics
- Biochemistry
- General Chemistry
- Atomic and Molecular Physics, and Optics
- Condensed Matter Physics
User-Defined Keywords
- Chemosensor
- Pentiptycene
- Responsive luminescence
- Spermine
- Tetraphenyl ethylene