Selective sensing of guanidinium and tetraalkylammonium ions using lipophilic cyclodextrins

Patricia M. Kelly, Ritu Kataky*, David Parker, Antonio F. Patti

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

23 Citations (Scopus)

Abstract

A range of lipophilic cyclodextrin derivatives, including 2,6-didodecyl-α- and -β-cyclodextrins, and 2,3,6-tri-O-ethyl-β- cyclodextrin, has been examined as ionophores in electrode response studies of the detection of guanidine, alkylated guanidines, creatinine and several tetraalkylammonium ions including choline, acetylcholine and the long-chain cationic surfactants CnH2n + 1NMe3+ (n = 8 → 16). Interference from Group Ia and IIa cations is minimal for alkylammonium ions (-log kpot > 4 typically) and in certain cases binding of the ion has been further defined by electrospray mass spectrometric and NMR methods.

Original languageEnglish
Pages (from-to)1955-1963
Number of pages9
JournalJournal of the Chemical Society, Perkin Transactions 2
Issue number11
DOIs
Publication statusPublished - Nov 1995

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