Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty

Keyphrases

• Active Ingredients 10%
• Aggregation Inhibitor 10%
• Alzheimer's Disease 30%
• Amorphous Structure 10%
• Amyloid-β Peptide 10%
• Cardiovascular Disease 10%
• Cerebrovascular Disease 10%
• Chinese Herbal Medicine 10%
• Circular Dichroism 10%
• Curcumin 10%
• Cytotoxic Effect 10%
• Cytotoxicity 10%
• Cytotoxity 100%
• Effects on Humans 10%
• Electron Microscope Study 10%
• Ferulic Acid 10%
• Fibril Aggregation 20%
• Fibril Formation 100%
• IC50 20%
• Immunoassay 10%
• Neural Cell Lines 10%
• Neuroblastoma SH-SY5Y Cells 10%
• Neuroprotection 10%
• Pathological Features 10%
• Preformed Fibrils 100%
• Salvia Miltiorrhiza 10%
• Salvianolic Acid B 100%
• Senile Plaques 10%
• Therapeutic Potential 10%
• Thioflavin T 10%
• Wrinkling 10%

Biochemistry, Genetics and Molecular Biology

• Amyloid Protein 50%
• Animal Model 50%
• Circular Dichroism 50%
• Cytotoxicity 100%
• Electron Microscope 50%
• Ferulic Acid 50%
• Fluorescence Assay 50%
• IC50 100%
• Immunoassay 50%
• Salvia Miltiorrhiza 50%
• Senile Plaque 50%
• Thioflavin 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Alzheimer's Disease 30%
• Amyloid Protein 10%
• Cardiovascular Disease 10%
• Cerebrovascular Disease 10%
• Curcumin 10%
• Cytotoxicity 20%
• Ferulic Acid 10%
• Fluorescence Assay 10%
• IC50 20%
• Immunoassay 10%
• Neuroblastoma 10%
• Neuroprotection 10%
• Salvia Miltiorrhiza 10%
• Salvianolic Acid B 100%
• Senile Plaque 10%
• Thioflavine 10%