S100A8 and S100A9 Are Associated with Doxorubicin-Induced Cardiotoxicity in the Heart of Diabetic Mice

Keyphrases

• Doxorubicin 100%
• Diabetic Mice 100%
• S100A8 100%
• Doxorubicin-induced Cardiotoxicity 100%
• S100A9 100%
• Diabetic Heart 72%
• Db Mouse 27%
• Type 2 Diabetic 27%
• Cancer Patients 18%
• Microarray Analysis 18%
• Non-diabetic 18%
• Doxorubicin-induced Cardiomyopathy 18%
• Molecular Signaling Pathways 18%
• Cardiomyopathy 18%
• Fractional Shortening 18%
• Oxidative Stress 9%
• Quantitative PCR 9%
• Cardiac Function 9%
• Inflammatory Response 9%
• NF-B 9%
• Expression Pattern 9%
• Age-matched 9%
• Signaling Mechanism 9%
• Microarray 9%
• Clinical Information 9%
• Diabetic 9%
• Cardiac Contractility 9%
• P38 MAPK Pathway 9%
• Type 2 Diabetic Patients 9%
• Intraperitoneal Injection 9%
• Specific Expression 9%
• Ketamine 9%
• Oxidative Metabolism 9%
• Regulatory Genes 9%
• Doxorubicin Treatments 9%
• Clinical Problems 9%
• Damaging Effects 9%
• IL-6 Level 9%
• Diabetic Model 9%
• Cardiac Injury 9%
• Cardiac Remodeling 9%
• Diabetic Cardiomyopathy 9%
• Euthanized 9%
• Xylazine 9%
• S100A8/9 9%
• Cardiac Inflammation 9%
• Transthoracic Echocardiography 9%
• Transcriptional Profile 9%

Medicine and Dentistry

• Cardiotoxicity 100%
• Doxorubicin 100%
• Diabetes Mellitus 52%
• Myocardial Disease 23%
• Cell Signaling Pathway 11%
• Malignant Neoplasm 11%
• Microarray Analysis 11%
• Oxidative Stress 5%
• Real Time Polymerase Chain Reaction 5%
• Interleukin 6 5%
• Serositis 5%
• Antiinfective Agent 5%
• Intraperitoneal Drug Administration 5%
• Aerobic Metabolism 5%
• Heart Function 5%
• MAPK Signaling 5%
• p38 Mitogen-Activated Protein Kinase 5%
• Regulator Gene 5%
• Heart Injury 5%
• Heart Ventricle Remodeling 5%
• Signaling Mechanism 5%
• Transthoracic Echocardiography 5%
• Contractile Function 5%
• Diabetic Cardiomyopathy 5%
• Xylazine 5%
• Carditis 5%
• Ketamine 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Cardiotoxicity 100%
• Doxorubicin 100%
• Diabetes Mellitus 52%
• Myocardial Disease 23%
• Malignant Neoplasm 11%
• Db/Db Mouse 11%
• Interleukin 6 5%
• Inflammation 5%
• Antiinfective Agent 5%
• Chemotherapy 5%
• Toxic Injury 5%
• Intraperitoneal Injection 5%
• Heart Injury 5%
• Ketamine 5%
• Heart Ventricle Remodeling 5%
• Diabetic Cardiomyopathy 5%
• Xylazine 5%
• Carditis 5%