Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

Guo Lin; Chaohong Gao; Qiong Zheng; Zhixian Lei; Huijuan Geng; Zian Lin; Huanghao Yang; Zongwei Cai

doi:10.1039/c7cc00482f

Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

Guo Lin, Chaohong Gao, Qiong Zheng, Zhixian Lei, Huijuan Geng, Zian Lin^*, Huanghao Yang, Zongwei Cai

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

163 Citations (Scopus)

Abstract

Core-shell structured magnetic covalent organic frameworks (Fe₃O₄@COFs) were synthesized via a facile approach at room temperature. Combining the advantages of high porosity, magnetic responsiveness, chemical stability and selectivity, Fe₃O₄@COFs can serve as an ideal absorbent for the highly efficient enrichment of peptides and the simultaneous exclusion of proteins from complex biological samples.

Original language	English
Pages (from-to)	3649-3652
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	26
DOIs	https://doi.org/10.1039/c7cc00482f
Publication status	Published - 2017

Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c7cc00482f

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title = "Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins",

abstract = "Core-shell structured magnetic covalent organic frameworks (Fe3O4@COFs) were synthesized via a facile approach at room temperature. Combining the advantages of high porosity, magnetic responsiveness, chemical stability and selectivity, Fe3O4@COFs can serve as an ideal absorbent for the highly efficient enrichment of peptides and the simultaneous exclusion of proteins from complex biological samples.",

author = "Guo Lin and Chaohong Gao and Qiong Zheng and Zhixian Lei and Huijuan Geng and Zian Lin and Huanghao Yang and Zongwei Cai",

note = "Funding Information: This work was supported by the National Natural Science Foundation of China (21375018 and 21675025), the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT15R11), and the Collaborative Research Fund from the Hong Kong Research Grant Council (C2024-14EF).",

year = "2017",

doi = "10.1039/c7cc00482f",

language = "English",

volume = "53",

pages = "3649--3652",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

AU - Lin, Guo

AU - Gao, Chaohong

AU - Zheng, Qiong

AU - Lei, Zhixian

AU - Geng, Huijuan

AU - Lin, Zian

AU - Yang, Huanghao

AU - Cai, Zongwei

N1 - Funding Information: This work was supported by the National Natural Science Foundation of China (21375018 and 21675025), the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT15R11), and the Collaborative Research Fund from the Hong Kong Research Grant Council (C2024-14EF).

PY - 2017

Y1 - 2017

N2 - Core-shell structured magnetic covalent organic frameworks (Fe3O4@COFs) were synthesized via a facile approach at room temperature. Combining the advantages of high porosity, magnetic responsiveness, chemical stability and selectivity, Fe3O4@COFs can serve as an ideal absorbent for the highly efficient enrichment of peptides and the simultaneous exclusion of proteins from complex biological samples.

AB - Core-shell structured magnetic covalent organic frameworks (Fe3O4@COFs) were synthesized via a facile approach at room temperature. Combining the advantages of high porosity, magnetic responsiveness, chemical stability and selectivity, Fe3O4@COFs can serve as an ideal absorbent for the highly efficient enrichment of peptides and the simultaneous exclusion of proteins from complex biological samples.

UR - http://www.scopus.com/inward/record.url?scp=85016303395&partnerID=8YFLogxK

U2 - 10.1039/c7cc00482f

DO - 10.1039/c7cc00482f

M3 - Journal article

C2 - 28304044

AN - SCOPUS:85016303395

SN - 1359-7345

VL - 53

SP - 3649

EP - 3652

JO - Chemical Communications

JF - Chemical Communications

IS - 26

ER -

Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

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