Abstract
A highly efficient Rh(I)/(S)-xyl-Binap catalytic system is developed for the asymmetric hydroselenation of various nonpolar olefins with diselenides. Under these mild reaction conditions, a wide range of heterobicyclic alkenes give selenol-incorporated adducts in excellent enantioselectivities (up to 97%) along with high yields (up to 96%) by overcoming self-promoted racemic hydroselenation. The strategy is also applied for kinetic resolution of unsymmetric oxabenzonorbornadiene.
Original language | English |
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Pages (from-to) | 2781-2785 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 22 |
Issue number | 7 |
Early online date | 20 Mar 2020 |
DOIs | |
Publication status | Published - 3 Apr 2020 |