Review of biological and pharmacological activities of the endemic taiwanese bitter medicinal mushroom, antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (Higher Basidiomycetes)

Patrick Y K YUE, Yi Yi Wong, Tony Yuk Kit Chan, Carman Ka Man Law, Yeuk Ki Tsoi, Kelvin S Y LEUNG

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Antrodia camphorata is an extremely rare fungus native to the forested regions of Taiwan. It is also a traditional Chinese medicine, and Taiwanese aborigines applied it for treating liver diseases and protecting from food and drug intoxication. Scientific studies have demonstrated that A. camphorata crude extracts and pure compounds possess a variety of beneficial functions, such as anti-hypertensive, anti-hyperlipidemic, anti-inflammatory, antioxidant, anti-tumor, and immuno-modulatory activities. Recent studies have shown that many of these biological and pharmacological activities can be attributed to various active constituents, including polysaccharides, terpenoids, steroids, lignans, benzoquinone derivatives, benzenoids, and maleic and succinic acid derivatives. A. camphorata has been considered as a novel phytotherapeutic agent. However, detailed mechanistic studies or even clinical trials on A. camphorata are still rare. With the help of modern analytical techniques, it is not surprising that many novel constituents are being identified or fractionated from A. camphorata mycelium and fruiting bodies. This review summarizes the latest published results from A. camphorata research, focusing on the biological and pharmacological activities of the crude extract and known constituents of A. camphorata.

Original languageEnglish
Pages (from-to)241-256
Number of pages16
JournalInternational Journal of Medicinal Mushrooms
Volume14
Issue number3
DOIs
Publication statusPublished - 2012

Scopus Subject Areas

  • Applied Microbiology and Biotechnology
  • Pharmacology
  • Drug Discovery

User-Defined Keywords

  • Anti-hypertensive
  • Anti-inflammatory
  • Anti-oxidant
  • Anti-tumor
  • Antrodia camphorata
  • Dietary supplements
  • Hepatoprotection
  • Immuno-modulatory activities
  • Medicinal mushrooms
  • Medicinal value

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