Review of adverse reactions to injections of Chinese materia medica

Zhaoxiang BIAN*, Hongcai Shang, Chungwah Cheng, Taixiang Wu, Youping Li, Boli Zhang

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Using Chinese Materia Medica (CM) as injections is an innovation that is proving effective in extensive clinical use in Mainland China. However, recent reports have focused on adverse reactions, ignoring the considerable successes of these preparations. In order to achieve balance in the media and in theminds of the public, we suggest the first step is to clarify the concepts of and differences between adverse drug reactions (ADR) and adverse events (AE) for all concerned-the public, medical practitioners, government officials, and lawmakers. Second, the State Food andDrugAdministration should raise the requirements for Chinese Materia Medica Injection (CMI) registration and license approval and emphasize the importance of evidence-based CMI development and evidence-based CMI license approval. Thirdly, drug companies and institutions should reinforce basic research about the quality control of herbs and CMI-drug interactions. Fourth, the Government should clarify the legal responsibilities for CMI approval agencies, CMI developers, medical doctors, and patients. Fifth, themedical association and Government should enhance training for health care professionals concerning the usage of CMIs. And finally sixth, State Food and Drug Administration should monitor the content and quality of the directions for use of CMI.

Original languageEnglish
Pages (from-to)88-94
Number of pages7
JournalJournal of Evidence-Based Medicine
Issue number2
Publication statusPublished - May 2010

Scopus Subject Areas

  • Health Policy

User-Defined Keywords

  • Chinese materia medica injection
  • Confidence
  • Crisis
  • Retrospection


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