Abstract
Previous neuroimaging studies have documented the structural damage in heroin addicts. However, little research has detailed the white matter microstructural changes in the human brain as a result of chronic heroin use and importantly, whether such changes can be recovered after short-term abstinence. Decreased fractional anisotropy values in frontal cortex were found in heroin users after 3 days of abstinence in comparison with controls. However, no significant difference was found between these heroin addicts and controls after 1-month abstinence. These results might better our understanding of the biological basis of drug addiction and provide insight into addiction treatment.
Original language | English |
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Pages (from-to) | 727-728 |
Number of pages | 2 |
Journal | Addiction Biology |
Volume | 18 |
Issue number | 4 |
DOIs | |
Publication status | Published - Jul 2013 |
User-Defined Keywords
- Cingulate gyrus
- diffusion tensor imaging
- fractional anisotropy
- frontal gyrus
- heroin addiction
- white matter