Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex

Guochen Bao; Shuai Zha; Zhenyu Liu; Yan Ho Fung; Chi Fai Chan; Hongguang Li; Pak Ho Chu; Dayong Jin; Peter A. Tanner; Ka-Leung Wong

doi:10.1021/acs.inorgchem.7b02243

Reversible and Sensitive Hg²⁺ Detection by a Cell-Permeable Ytterbium Complex

Guochen Bao
, Shuai Zha
, Zhenyu Liu
, Yan Ho Fung
, Chi Fai Chan
, Hongguang Li
, Pak Ho Chu
, Dayong Jin^*
, Peter A. Tanner^*
, Ka-Leung Wong^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

32 Citations (Scopus)

Abstract

A cell-permeable ytterbium complex shows reversible binding with Hg²⁺ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg²⁺ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg²⁺ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.

Original language	English
Pages (from-to)	120-128
Number of pages	9
Journal	Inorganic Chemistry
Volume	57
Issue number	1
Early online date	11 Dec 2017
DOIs	https://doi.org/10.1021/acs.inorgchem.7b02243
Publication status	Published - 2 Jan 2018

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title = "Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex",

abstract = "A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.",

author = "Guochen Bao and Shuai Zha and Zhenyu Liu and Fung, \{Yan Ho\} and Chan, \{Chi Fai\} and Hongguang Li and Chu, \{Pak Ho\} and Dayong Jin and Tanner, \{Peter A.\} and Ka-Leung Wong",

note = "Funding Information: This work was funded by grants from The Hong Kong Research Grants Council (HKBU 22301615) and Hong Kong Baptist University (FRG 1/16-17/016 and SDF 15-0324-P03).",

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doi = "10.1021/acs.inorgchem.7b02243",

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T1 - Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex

AU - Bao, Guochen

AU - Zha, Shuai

AU - Liu, Zhenyu

AU - Fung, Yan Ho

AU - Chan, Chi Fai

AU - Li, Hongguang

AU - Chu, Pak Ho

AU - Jin, Dayong

AU - Tanner, Peter A.

AU - Wong, Ka-Leung

N1 - Funding Information: This work was funded by grants from The Hong Kong Research Grants Council (HKBU 22301615) and Hong Kong Baptist University (FRG 1/16-17/016 and SDF 15-0324-P03).

PY - 2018/1/2

Y1 - 2018/1/2

N2 - A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.

AB - A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.

UR - https://www.scopus.com/pages/publications/85040121606

U2 - 10.1021/acs.inorgchem.7b02243

DO - 10.1021/acs.inorgchem.7b02243

M3 - Journal article

C2 - 29227641

AN - SCOPUS:85040121606

SN - 0020-1669

VL - 57

SP - 120

EP - 128

JO - Inorganic Chemistry

JF - Inorganic Chemistry

IS - 1

ER -

Reversible and Sensitive Hg²⁺ Detection by a Cell-Permeable Ytterbium Complex

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