Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex

Guochen Bao, Shuai Zha, Zhenyu Liu, Yan Ho Fung, Chi Fai Chan, Hongguang Li, Pak Ho Chu, Dayong Jin*, Peter A. Tanner*, Ka-Leung Wong*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

29 Citations (Scopus)


A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.

Original languageEnglish
Pages (from-to)120-128
Number of pages9
JournalInorganic Chemistry
Issue number1
Early online date11 Dec 2017
Publication statusPublished - 2 Jan 2018

Scopus Subject Areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry


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