Responsive and mitochondria-specific ruthenium(ii) complex for dual in vitro applications: Two-photon (near-infrared) induced imaging and regioselective cell killing

Hanzhong Ke, Hongda Wang, Rick W K WONG*, Nai Ki MAK, Daniel W J KWONG, Ka-Leung WONG, Hoi Lam TAM

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

A mitochondria-permeable ruthenium(ii) complex has been designed as a responsive probe which may be used to sensitize the formation of singlet oxygen (ΦΔ = 0.93) and cause local damage in cellulo when exposed to UV and near-infrared laser excitation.

Original languageEnglish
Pages (from-to)6678-6680
Number of pages3
JournalChemical Communications
Volume46
Issue number36
DOIs
Publication statusPublished - 28 Sep 2010

Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Responsive and mitochondria-specific ruthenium(ii) complex for dual in vitro applications: Two-photon (near-infrared) induced imaging and regioselective cell killing'. Together they form a unique fingerprint.

Cite this