TY - JOUR
T1 - Research trends and prospects on brain metastasis from breast cancer
T2 - A bibliometric analysis
AU - Wu, Si Qi
AU - Liu, Yan
AU - Zhou, Jie
AU - You, Yan Ting
AU - Zhou, Xing Hong
AU - Chen, Li Qian
AU - Kwan, Hiu Yee
AU - Zhao, Xiao Shan
AU - Wu, Yi Fen
AU - Liu, Yan Yan
N1 - Funding Information:
This work was supported by the National Natural Science Foundation of China ( 81873205, 81803877, 82104629, 81904037), the Natural Science Foundation of Guangdong Province, China (2020B1515120063) and Postdoctoral Science Foundation of China (NO. 2022M711536).
Publisher Copyright:
© 2023 Wu, Liu, Zhou, You, Zhou, Chen, Kwan, Zhao, Wu and Liu.
PY - 2023/4/5
Y1 - 2023/4/5
N2 - Introduction: Brain metastasis is the terminal event of breast cancer with poor prognoses. Therefore, this article aimed to provide an updated summary on the development, hotspots, and research trends of brain metastasis from breast cancer based on bibliometric analysis.Method: Publications on breast cancer with brain metastasis retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, and other online bibliometric analysis platforms were used to analyze and visualize the result.Result: In totality, 693 researchers from 3,623 institutions across 74 counties and regions published a total of 2,790 papers in 607 journals. There was a noticeable increase in publications in 2006. The United States was the dominant country with the most publications followed by China. University Texas MD Anderson Cancer Center was the most productive institution, while Dana Farber Cancer Institution was the most cited. Journal of Neuro-Oncology published the most papers, while Journal of Clinical Oncology ranked first based on cocited analysis. Nancy U. Lin was the most productive and cited author with high influence. There was a focus on basic research, clinical trials, local therapy, treatment optimization, and epidemiological studies regarding brain metastases from breast cancer. References focused on pathogenesis, prevention, treatment, and prognosis were cited most frequently, among which the clinical trial of novel treatment attracted most attention from researchers. Reference citation burst detection suggested that new therapies such as the novel tyrosine kinase inhibitor and antibody–drug conjugate may lead the research trends in the future.Conclusion: High-income countries contributed more to the field of breast cancer with brain metastasis, while developing countries like China developed quickly. Furthermore, the success of novel therapies in recent years may lead to the new era of treatment of breast cancer with brain metastasis in the future.
AB - Introduction: Brain metastasis is the terminal event of breast cancer with poor prognoses. Therefore, this article aimed to provide an updated summary on the development, hotspots, and research trends of brain metastasis from breast cancer based on bibliometric analysis.Method: Publications on breast cancer with brain metastasis retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, and other online bibliometric analysis platforms were used to analyze and visualize the result.Result: In totality, 693 researchers from 3,623 institutions across 74 counties and regions published a total of 2,790 papers in 607 journals. There was a noticeable increase in publications in 2006. The United States was the dominant country with the most publications followed by China. University Texas MD Anderson Cancer Center was the most productive institution, while Dana Farber Cancer Institution was the most cited. Journal of Neuro-Oncology published the most papers, while Journal of Clinical Oncology ranked first based on cocited analysis. Nancy U. Lin was the most productive and cited author with high influence. There was a focus on basic research, clinical trials, local therapy, treatment optimization, and epidemiological studies regarding brain metastases from breast cancer. References focused on pathogenesis, prevention, treatment, and prognosis were cited most frequently, among which the clinical trial of novel treatment attracted most attention from researchers. Reference citation burst detection suggested that new therapies such as the novel tyrosine kinase inhibitor and antibody–drug conjugate may lead the research trends in the future.Conclusion: High-income countries contributed more to the field of breast cancer with brain metastasis, while developing countries like China developed quickly. Furthermore, the success of novel therapies in recent years may lead to the new era of treatment of breast cancer with brain metastasis in the future.
KW - ADC (antibody-drug conjugate)
KW - bibliometric analysis
KW - brain metastasis
KW - breast cancer
KW - research trend
KW - TKI (tyrosine kinase inhibitor)
UR - http://www.scopus.com/inward/record.url?scp=85153510549&partnerID=8YFLogxK
U2 - 10.3389/fonc.2023.1091249
DO - 10.3389/fonc.2023.1091249
M3 - Journal article
AN - SCOPUS:85153510549
SN - 2234-943X
VL - 13
JO - Frontiers in Oncology
JF - Frontiers in Oncology
M1 - 1091249
ER -
