TY - JOUR
T1 - Research and development of proteins and peptides with therapeutic potential from yam tubers
AU - Zhang, Liang
AU - Ng, Tzi Bun
AU - Lam, Jenny Ka Wing
AU - Wang, Shi Wei
AU - Lao, Lixing
AU - Zhang, Kalin Yanbo
AU - SZE, Cho Wing
N1 - Funding Information:
This study was partially supported by grants from the Innovation and Technology Fund (ITF), Innovation and Technology Commission, Government of Hong Kong Special Administrative Region (Project no ITS/262/09FP), and Seed Funding Programme for Basic Research, the University of Hong Kong (Project codes: 201411159213 and 201211159146).
PY - 2019/3
Y1 - 2019/3
N2 - We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.
AB - We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.
KW - Anti-cancer
KW - Anti-microbial
KW - Anti-oxidation
KW - Immunomodulation
KW - Medicinal yam
KW - Menopause
KW - Peptides
KW - Proteins
UR - http://www.scopus.com/inward/record.url?scp=85059797120&partnerID=8YFLogxK
U2 - 10.2174/1389203719666180622094356
DO - 10.2174/1389203719666180622094356
M3 - Journal article
C2 - 29932033
AN - SCOPUS:85059797120
SN - 1389-2037
VL - 20
SP - 277
EP - 284
JO - Current Protein and Peptide Science
JF - Current Protein and Peptide Science
IS - 3
ER -
