Research and development of proteins and peptides with therapeutic potential from yam tubers

Liang Zhang, Tzi Bun Ng, Jenny Ka Wing Lam, Shi Wei Wang, Lixing Lao, Kalin Yanbo Zhang, Cho Wing SZE*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.

Original languageEnglish
Pages (from-to)277-284
Number of pages8
JournalCurrent Protein and Peptide Science
Volume20
Issue number3
DOIs
Publication statusPublished - 2019

Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

User-Defined Keywords

  • Anti-cancer
  • Anti-microbial
  • Anti-oxidation
  • Immunomodulation
  • Medicinal yam
  • Menopause
  • Peptides
  • Proteins

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