@article{83b4a791f081413289aa43f38c13af7b,
title = "Recent Progress and Development of G-Quadruplex-Based Luminescent Assays for Ochratoxin A Detection",
abstract = "Ochratoxin A (OTA) is a mycotoxin that is widespread throughout the world. It contaminates foods such as vegetables, fruits, and rice. It harms human health and has potential carcinogenic effects. The G-quadruplex (G4) is a tetraplexed DNA structure generated from guanine-rich DNA that has found emerging use in aptamer-based sensing systems. This review outlines the status of OTA contamination and conventional detection methods for OTA. Various G4-based methods to detect OTA developed in recent years are summarized along with their advantages and disadvantages compared to existing approaches.",
keywords = "aptamer, food safety, G-quadruplex, nucleic acid detection, ochratoxin A",
author = "Nao, {Sang Cuo} and Wu, {Ke Jia} and Wanhe Wang and Leung, {Chung Hang} and Ma, {Edmond Dik Lung}",
note = "Funding Information: Funding. This work was supported by Hong Kong Baptist University (FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the National Natural Science Foundation of China (21575121 and 21775131), the Hong Kong Baptist University Century Club Sponsorship Scheme 2019 and 2020, the Interdisciplinary Research Matching Scheme (RC-IRMS/16- 17/03), Interdisciplinary Research Clusters Matching Scheme (RC-IRCs/17-18/03), Collaborative Research Fund (C5026- 16G), SKLEBA and HKBU Strategic Development Fund (SKLP_1920_P02), the Science and Technology Development Fund, Macau SAR (File no. 0072/2018/A2), and the University of Macau (MYRG2018-00187-ICMS and MYRG-2019- 00002-ICMS).",
year = "2020",
month = sep,
day = "1",
doi = "10.3389/fchem.2020.00767",
language = "English",
volume = "8",
journal = "Frontiers in Chemistry",
issn = "2296-2646",
publisher = "Frontiers Media S.A.",
}
