TY - JOUR
T1 - Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics
AU - Ye, Zhaoyi
AU - Bao, Ying
AU - Chen, Zefeng
AU - Ye, Huiling
AU - Feng, Zhenzhen
AU - Li, Yushan
AU - Zeng, Yaoxun
AU - Pan, Zhenxing
AU - Ouyang, Defang
AU - Zhang, Kun
AU - Liu, Xujie
AU - He, Yan
N1 - Funding Information:
Zhaoyi Ye and Ying Bao contributed equally to this work. This work was supported by the National Natural Science Foundation of China (No. 32171314), Guangdong Basic and Applied Basic Research Foundation (No. 2022A1515010671), Guangzhou Basic and Applied Basic Research Foundation (No. 202201010371) and University Innovative Team Support for Major Chronic Diseases and Drug Development (26330320901).
Publisher Copyright:
© 2024 Elsevier B.V. All rights reserved.
PY - 2024/4/1
Y1 - 2024/4/1
N2 - Cancer is an extremely significant disease that profoundly impacts human survival and quality of life. Researchers have been searching for effective therapies, among which metal/organic hybrid nanomaterials received widespread attention due to their tumor imaging and treatment capabilities. Metal/organic hybrid nanomaterials are easy to modify and possess magnetic and plasma resonance, catalytic function, and biological activity. Then, researchers have recently designed a series of highly efficient metal/organic hybrid nanomaterials with integrated theranostics, good biocompatibility, and relative safety for achieving excellent therapeutic outcomes in cancer combined with various treatment methods. This paper highlights the research progress of metal/organic hybrid nanomaterials in the single diagnosis and treatment of cancer and their integration into diagnosis and treatment. The development trends, key problems, future outlook, and challenges of metal/organic hybrid nanomaterials are summarized and discussed. It is expected that the metal nanoparticles discussed in this paper can provide insights into the early diagnosis and effective treatment of cancer.
AB - Cancer is an extremely significant disease that profoundly impacts human survival and quality of life. Researchers have been searching for effective therapies, among which metal/organic hybrid nanomaterials received widespread attention due to their tumor imaging and treatment capabilities. Metal/organic hybrid nanomaterials are easy to modify and possess magnetic and plasma resonance, catalytic function, and biological activity. Then, researchers have recently designed a series of highly efficient metal/organic hybrid nanomaterials with integrated theranostics, good biocompatibility, and relative safety for achieving excellent therapeutic outcomes in cancer combined with various treatment methods. This paper highlights the research progress of metal/organic hybrid nanomaterials in the single diagnosis and treatment of cancer and their integration into diagnosis and treatment. The development trends, key problems, future outlook, and challenges of metal/organic hybrid nanomaterials are summarized and discussed. It is expected that the metal nanoparticles discussed in this paper can provide insights into the early diagnosis and effective treatment of cancer.
KW - Cancer theranostics
KW - Metal/organic hybrid nanomaterials
KW - Organic ligand
UR - http://www.scopus.com/inward/record.url?scp=85184751587&partnerID=8YFLogxK
U2 - 10.1016/j.ccr.2023.215654
DO - 10.1016/j.ccr.2023.215654
M3 - Journal article
AN - SCOPUS:85184751587
SN - 0010-8545
VL - 504
JO - Coordination Chemistry Reviews
JF - Coordination Chemistry Reviews
M1 - 215654
ER -
