Recent Advances in Inorganic Chiral Nanomaterials

Junjun Liu, Lin Yang, Ping Qin, Shiqing Zhang, Ken Kin Lam Yung, Jeffery Huang*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

53 Citations (Scopus)


Inorganic nanoparticles offer a multifunctional platform for biomedical applications in drug delivery, biosensing, bioimaging, disease diagnosis, screening, and therapies. Homochirality prevalently exists in biological systems composed of asymmetric biochemical activities and processes, so biomedical applications essentially favor the usage of inorganic chiral nanomaterials, which have been widely studied in the past two decades. Here, the latest investigations are summarized including the characterization of 3D stereochirality, the bionic fabrication of hierarchical chirality, extension of the compositional space to poly-elements, studying optical activities with the (sub-)single-particle resolution, and the experimental demonstration in biomedical applications. These advanced studies pave the way toward fully understanding the two important chiral effects (i.e., the chiroptical and enantioselective effects), and prospectively promote the flexible design and fabrication of inorganic chiral nanoparticles with engineerable functionalities to solve diverse practical problems closely associated with environment and public health.

Original languageEnglish
Article number2005506
Number of pages12
JournalAdvanced Materials
Issue number50
Early online date17 Feb 2021
Publication statusPublished - 16 Dec 2021

Scopus Subject Areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

User-Defined Keywords

  • chiral nanomaterials
  • chirality
  • enantioselectivity
  • inorganic nanomaterials
  • optical activity


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