TY - JOUR
T1 - Recent Advances in Inorganic Chiral Nanomaterials
AU - Liu, Junjun
AU - Yang, Lin
AU - Qin, Ping
AU - Zhang, Shiqing
AU - Yung, Ken Kin Lam
AU - Huang, Jeffery
N1 - Funding Information:
J.J.L., L.Y., and P.Q. contributed equally to this work. This work was financially supported by NSFC/91856127, NSFC/22075239, GRF/12200118, GRF/12302320, and SKLP_1920_P06 (HKBU).
PY - 2021/12/16
Y1 - 2021/12/16
N2 - Inorganic nanoparticles offer a multifunctional platform for biomedical applications in drug delivery, biosensing, bioimaging, disease diagnosis, screening, and therapies. Homochirality prevalently exists in biological systems composed of asymmetric biochemical activities and processes, so biomedical applications essentially favor the usage of inorganic chiral nanomaterials, which have been widely studied in the past two decades. Here, the latest investigations are summarized including the characterization of 3D stereochirality, the bionic fabrication of hierarchical chirality, extension of the compositional space to poly-elements, studying optical activities with the (sub-)single-particle resolution, and the experimental demonstration in biomedical applications. These advanced studies pave the way toward fully understanding the two important chiral effects (i.e., the chiroptical and enantioselective effects), and prospectively promote the flexible design and fabrication of inorganic chiral nanoparticles with engineerable functionalities to solve diverse practical problems closely associated with environment and public health.
AB - Inorganic nanoparticles offer a multifunctional platform for biomedical applications in drug delivery, biosensing, bioimaging, disease diagnosis, screening, and therapies. Homochirality prevalently exists in biological systems composed of asymmetric biochemical activities and processes, so biomedical applications essentially favor the usage of inorganic chiral nanomaterials, which have been widely studied in the past two decades. Here, the latest investigations are summarized including the characterization of 3D stereochirality, the bionic fabrication of hierarchical chirality, extension of the compositional space to poly-elements, studying optical activities with the (sub-)single-particle resolution, and the experimental demonstration in biomedical applications. These advanced studies pave the way toward fully understanding the two important chiral effects (i.e., the chiroptical and enantioselective effects), and prospectively promote the flexible design and fabrication of inorganic chiral nanoparticles with engineerable functionalities to solve diverse practical problems closely associated with environment and public health.
KW - chiral nanomaterials
KW - chirality
KW - enantioselectivity
KW - inorganic nanomaterials
KW - optical activity
UR - http://www.scopus.com/inward/record.url?scp=85100975395&partnerID=8YFLogxK
U2 - 10.1002/adma.202005506
DO - 10.1002/adma.202005506
M3 - Journal article
AN - SCOPUS:85100975395
SN - 0935-9648
VL - 33
JO - Advanced Materials
JF - Advanced Materials
IS - 50
M1 - 2005506
ER -