Rearranged taxanes from the bark of Taxus yunnanensis

Sheng Hong Li; Hong Jie Zhang; Ping Yao; Han Dong Sun; Harry H.S. Fong

doi:10.1021/np000118t

Rearranged taxanes from the bark of Taxus yunnanensis

Sheng Hong Li, Hong Jie Zhang^*, Ping Yao, Han Dong Sun, Harry H.S. Fong

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

21 Citations (Scopus)

Abstract

Five new 11(15→1)-abeo-taxane diterpenoids, taxuyunnanines K-O (1-5), were isolated from an ethanol extract of the bark of Taxus yunnanensis, and their structures were determined using MS and NMR techniques. Compounds 1/2 and 4/5 are rearranged taxane diterpenoids possessing an opened oxetane ring moiety at C4(20). Compounds 4/5 are rearranged taxoids lacking an oxygenated functionality at C-4.

Original language	English
Pages (from-to)	1488-1491
Number of pages	4
Journal	Journal of Natural Products
Volume	63
Issue number	11
DOIs	https://doi.org/10.1021/np000118t
Publication status	Published - Nov 2000

Scopus Subject Areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np000118t

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title = "Rearranged taxanes from the bark of Taxus yunnanensis",

abstract = "Five new 11(15→1)-abeo-taxane diterpenoids, taxuyunnanines K-O (1-5), were isolated from an ethanol extract of the bark of Taxus yunnanensis, and their structures were determined using MS and NMR techniques. Compounds 1/2 and 4/5 are rearranged taxane diterpenoids possessing an opened oxetane ring moiety at C4(20). Compounds 4/5 are rearranged taxoids lacking an oxygenated functionality at C-4.",

author = "Li, {Sheng Hong} and Zhang, {Hong Jie} and Ping Yao and Sun, {Han Dong} and Fong, {Harry H.S.}",

note = "This project was supported by grants from the National Science Foundation of China (3950081), the Young Academic and Technical Leader Raising Foundation of 11 Yunnan Province (awarded to H.-J.Z.), and the Special Supported Biosciences and Biotechniques Foundation of Academia Sinica (STZ-11). ",

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doi = "10.1021/np000118t",

language = "English",

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AU - Li, Sheng Hong

AU - Zhang, Hong Jie

AU - Yao, Ping

AU - Sun, Han Dong

AU - Fong, Harry H.S.

N1 - This project was supported by grants from the National Science Foundation of China (3950081), the Young Academic and Technical Leader Raising Foundation of 11 Yunnan Province (awarded to H.-J.Z.), and the Special Supported Biosciences and Biotechniques Foundation of Academia Sinica (STZ-11).

PY - 2000/11

Y1 - 2000/11

N2 - Five new 11(15→1)-abeo-taxane diterpenoids, taxuyunnanines K-O (1-5), were isolated from an ethanol extract of the bark of Taxus yunnanensis, and their structures were determined using MS and NMR techniques. Compounds 1/2 and 4/5 are rearranged taxane diterpenoids possessing an opened oxetane ring moiety at C4(20). Compounds 4/5 are rearranged taxoids lacking an oxygenated functionality at C-4.

AB - Five new 11(15→1)-abeo-taxane diterpenoids, taxuyunnanines K-O (1-5), were isolated from an ethanol extract of the bark of Taxus yunnanensis, and their structures were determined using MS and NMR techniques. Compounds 1/2 and 4/5 are rearranged taxane diterpenoids possessing an opened oxetane ring moiety at C4(20). Compounds 4/5 are rearranged taxoids lacking an oxygenated functionality at C-4.

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JO - Journal of Natural Products

JF - Journal of Natural Products

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ER -

Rearranged taxanes from the bark of Taxus yunnanensis

Abstract

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