Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex

Hongguang Li; Rongfeng Lan; Chi Fai Chan; Lijun Jiang; Lixiong Dai; Daniel W.J. Kwong; Michael Hon Wah Lam; Ka Leung Wong

doi:10.1039/c5cc05461c

Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex

Hongguang Li
, Rongfeng Lan
, Chi Fai Chan
, Lijun Jiang
, Lixiong Dai
, Daniel W.J. Kwong^*
, Michael Hon Wah Lam
, Ka Leung Wong

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

48 Citations (Scopus)

Abstract

A water-soluble light-responsive antitumor agent, PtEuL, based on a cisplatin-linked europium-cyclen complex has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on and long-lived europium emission as a responsive traceable signal.

Original language	English
Pages (from-to)	14022-14025
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	74
DOIs	https://doi.org/10.1039/c5cc05461c
Publication status	Published - 30 Jul 2015

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10.1039/c5cc05461c

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@article{911def481d1c4daea93d58d74964847c,

title = "Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex",

abstract = "A water-soluble light-responsive antitumor agent, PtEuL, based on a cisplatin-linked europium-cyclen complex has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on and long-lived europium emission as a responsive traceable signal.",

author = "Hongguang Li and Rongfeng Lan and Chan, \{Chi Fai\} and Lijun Jiang and Lixiong Dai and Kwong, \{Daniel W.J.\} and Lam, \{Michael Hon Wah\} and Wong, \{Ka Leung\}",

note = "The work described in this communication was supported by grants from the HKRGC (HKBU 203012) and HKBU (FRG1/14-15/015). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2015",

month = jul,

day = "30",

doi = "10.1039/c5cc05461c",

language = "English",

volume = "51",

pages = "14022--14025",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex

AU - Li, Hongguang

AU - Lan, Rongfeng

AU - Chan, Chi Fai

AU - Jiang, Lijun

AU - Dai, Lixiong

AU - Kwong, Daniel W.J.

AU - Lam, Michael Hon Wah

AU - Wong, Ka Leung

N1 - The work described in this communication was supported by grants from the HKRGC (HKBU 203012) and HKBU (FRG1/14-15/015). Publisher Copyright: © The Royal Society of Chemistry.

PY - 2015/7/30

Y1 - 2015/7/30

N2 - A water-soluble light-responsive antitumor agent, PtEuL, based on a cisplatin-linked europium-cyclen complex has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on and long-lived europium emission as a responsive traceable signal.

AB - A water-soluble light-responsive antitumor agent, PtEuL, based on a cisplatin-linked europium-cyclen complex has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on and long-lived europium emission as a responsive traceable signal.

UR - https://www.scopus.com/pages/publications/84940878636

U2 - 10.1039/c5cc05461c

DO - 10.1039/c5cc05461c

M3 - Journal article

C2 - 26257074

AN - SCOPUS:84940878636

SN - 1359-7345

VL - 51

SP - 14022

EP - 14025

JO - Chemical Communications

JF - Chemical Communications

IS - 74

ER -

Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex

Abstract

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