Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

Xiao Bo Zhou; Wing Hong Chan; Albert W.M. Lee; Chi Chung Yeung

doi:10.3762/bjoc.7.176

Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

Xiao Bo Zhou
, Wing Hong Chan^*
, Albert W.M. Lee
, Chi Chung Yeung

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

13 Citations (Scopus)

Abstract

A ratiometric fluorescent probe based on a Cd²⁺-ACAQ complex was designed and demonstrated for the chemo-and enantioselective detection of cysteine in 99:1 buffered HEPES: ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.

Original language	English
Pages (from-to)	1508-1515
Number of pages	8
Journal	Beilstein Journal of Organic Chemistry
Volume	7
DOIs	https://doi.org/10.3762/bjoc.7.176
Publication status	Published - 9 Nov 2011

User-Defined Keywords

Chemosensor
D-cysteine
Enantioselectivity
Fluorescence
Ratiometric

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10.3762/bjoc.7.176

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@article{28a860e3322b4b71927b46a83c426588,

title = "Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution",

abstract = "A ratiometric fluorescent probe based on a Cd2+-ACAQ complex was designed and demonstrated for the chemo-and enantioselective detection of cysteine in 99:1 buffered HEPES: ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.",

keywords = "Chemosensor, D-cysteine, Enantioselectivity, Fluorescence, Ratiometric",

author = "Zhou, \{Xiao Bo\} and Chan, \{Wing Hong\} and Lee, \{Albert W.M.\} and Yeung, \{Chi Chung\}",

note = "The financial support of this work by the University Grants Committee of the Hong Kong SAR, China (HKBU 200208) is acknowledged.",

year = "2011",

month = nov,

day = "9",

doi = "10.3762/bjoc.7.176",

language = "English",

volume = "7",

pages = "1508--1515",

journal = "Beilstein Journal of Organic Chemistry",

issn = "1860-5397",

publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

TY - JOUR

T1 - Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

AU - Zhou, Xiao Bo

AU - Chan, Wing Hong

AU - Lee, Albert W.M.

AU - Yeung, Chi Chung

N1 - The financial support of this work by the University Grants Committee of the Hong Kong SAR, China (HKBU 200208) is acknowledged.

PY - 2011/11/9

Y1 - 2011/11/9

N2 - A ratiometric fluorescent probe based on a Cd2+-ACAQ complex was designed and demonstrated for the chemo-and enantioselective detection of cysteine in 99:1 buffered HEPES: ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.

AB - A ratiometric fluorescent probe based on a Cd2+-ACAQ complex was designed and demonstrated for the chemo-and enantioselective detection of cysteine in 99:1 buffered HEPES: ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.

KW - Chemosensor

KW - D-cysteine

KW - Enantioselectivity

KW - Fluorescence

KW - Ratiometric

UR - https://www.scopus.com/pages/publications/81255146845

U2 - 10.3762/bjoc.7.176

DO - 10.3762/bjoc.7.176

M3 - Journal article

AN - SCOPUS:81255146845

SN - 1860-5397

VL - 7

SP - 1508

EP - 1515

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

ER -

Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

Abstract

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