Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

Xiao Bo Zhou, Wing Hong CHAN*, Albert W M LEE, Chi Chung Yeung

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

A ratiometric fluorescent probe based on a Cd2+-ACAQ complex was designed and demonstrated for the chemo-and enantioselective detection of cysteine in 99:1 buffered HEPES: ACN solutions. Under the measuring conditions, the sensor demonstrates high selectivity toward Cys against Hcy and GSH, and an enantioselectivity of 3.35 can be achieved for antipodal forms of Cys.

Original languageEnglish
Pages (from-to)1508-1515
Number of pages8
JournalBeilstein Journal of Organic Chemistry
Volume7
DOIs
Publication statusPublished - 9 Nov 2011

Scopus Subject Areas

  • Organic Chemistry

User-Defined Keywords

  • Chemosensor
  • D-cysteine
  • Enantioselectivity
  • Fluorescence
  • Ratiometric

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