Rapid identification of Fritillariae Cirrhosae Bulbus and its adulterants by UPLC-ELSD fingerprint combined with chemometrics methods

Dandan Luo, Yuyu Liu, Yaping Wang, Xiaocan Zhang, Linfang Huang, Baozhong Duan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Fritillariae Cirrhosae Bulbus (FCB) is a well-known and precious antitussive traditional Chinese medical herb. It is prone to be accidentally contaminated, deliberately substituted or admixed with other species of similar morphological characters. These adulterations might cause quality confusion and safety issues. In this study, a UPLC-ELSD fingerprint analysis with chemometric methods, including similarity analysis, hierarchical clustering analysis, and principal component analysis, were applied for the identification of FCB and its adulterants. Our results indicated that the combined method could efficiently identify and distinguish FCB from its adulterations. The proposed method provides a potential perspective for the quality control of traditional Chinese medicine.

Original languageEnglish
Pages (from-to)46-51
Number of pages6
JournalBiochemical Systematics and Ecology
Volume76
DOIs
Publication statusPublished - Feb 2018

Scopus Subject Areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry

User-Defined Keywords

  • Adulterants
  • Chemometrics
  • Fingerprint analysis
  • Fritillariae Cirrhosae Bulbus
  • UPLC-ELSD

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