随机对照实况试验的概念、设计和实施

Translated title of the contribution: Randomized controlled pragmatic trial: concept, design, practice

吴泰相*, 商洪才, 卞兆祥

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

随机对照实况试验由于所纳入的受试者和干预过程接近临床实践的真实状况,其效应量接近或与临床实践真实情况相似,因此其疗效效应量用于评估患者的疗效较之辨析性研究更加准确。由于其特点是干预措施和过程可变,符合包括中医药和针灸在内的临床治疗特点,因而日益受到国内中医药界的极大兴趣和关注。实际上,随机对照实况试验也适合于比较采用临床路径和不采用临床路径管理患者的效果。本文介绍了随机对照实况试验的原理和概念,并通过举例说明其设计要点。

The two factors that affect enrollment of participants and the process of intervention in randomized controlled pragmatic trials are similar to the situation of clinical practice, thus its effects are similar to the situation of clinical practice. Therefore, when one estimates an intervention's effect on a patient, it will be more similar to a real clinical situation than results taken from an explanatory trial. Due to the introduction of interventions and process variables used in a pragmatic trial that conform to traditional Chinese medicine and acupuncture practices, more and more interest is growing among researchers in the traditional Chinese medicine field. This article introduces the principles and concepts of the pragmatic trial, and the key points of design via some samples.

Translated title of the contributionRandomized controlled pragmatic trial: concept, design, practice
Original languageChinese (Simplified)
Pages (from-to)1277-1280
Number of pages4
Journal中国循证医学杂志
Volume9
Issue number12
DOIs
Publication statusPublished - Dec 2009

Scopus Subject Areas

  • Medicine(all)

User-Defined Keywords

  • Chinese medicine
  • Clinical pathway
  • Pragmatic trial
  • Randomized controlled trial

Fingerprint

Dive into the research topics of 'Randomized controlled pragmatic trial: concept, design, practice'. Together they form a unique fingerprint.

Cite this