Quantitative comparison and metabolite profiling of saponins in different parts of the root of panax notoginseng

Jing Rong Wang, Lee Fong Yau, Wei Na Gao, Yong Liu, Pui Wing Yick, Liang LIU*, Zhi Hong JIANG

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

96 Citations (Scopus)


Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in "Chinese Pharmacopoeia", individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of different portions derived from the whole root, as well as commercial samples, were carried out, showing an overall higher content of saponins in rhizome, followed by main root, branch root, and fibrous root. Ginsenoside Rb2was proposed as a potential marker with a content of 0.5 mg/g as a threshold value for differentiating rhizome from other parts. Multivariate analysis of the metabolite profile further suggested 32 saponins as potential markers for the discrimination of different parts of notoginseng. Collectively, the study provided comprehensive chemical evidence for the distinct usage of different parts of notoginseng and, hence, is of great importance for the rational application and exploitation of individual parts of notoginseng.

Original languageEnglish
Pages (from-to)9024-9034
Number of pages11
JournalJournal of Agricultural and Food Chemistry
Issue number36
Publication statusPublished - 10 Sept 2014

Scopus Subject Areas

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

User-Defined Keywords

  • ginsenosides, LC-MS
  • metabolomics
  • notoginseng
  • root


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