Protopanaxatriol-type ginsenosides from the root of Panax ginseng

Guo Yuan Zhu, Ying Wei Li, Desmond Kwok Po Hau, Zhi Hong JIANG, Zhiling YU, David W F FONG*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

62 Citations (Scopus)


Ginseng, the root of Panax ginseng C. A. Meyer (Araliaceae), is one of the most important traditional medicines and functional foods. A detailed phytochemical investigation on the roots of P. ginseng led to the isolation of 6 new natural protopanaxatriol (PPT)-type ginsenosides, ginsenosides Re 1-Re6 (compounds 1-6), along with 10 known PPT-type ginsenosides. Their structures were elucidated on the basis of chemical and spectroscopic analyses, including high-resolution mass spectrometry (HRMS) and 1D and 2D nuclear magnetic resonance (NMR). The unusual α-d- glucopyranosyl-(1→3)-β-d-glucopyranosyl sugar chain, as found in compounds 1 and 2, is reported in the genus Panax for the first time.

Original languageEnglish
Pages (from-to)200-205
Number of pages6
JournalJournal of Agricultural and Food Chemistry
Issue number1
Publication statusPublished - 12 Jan 2011

Scopus Subject Areas

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

User-Defined Keywords

  • Araliaceae
  • ginsenoside
  • ginsenosides Re-Re
  • Panax ginseng
  • protopanaxatriol


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