Promoting the Quality and Transparency of Health Research in China

Yanfang Ma, Qi Wang, Yuting Duan, Qianling Shi, Xuan Zhang, Kehu Yang, Youping Li, David Moher, Yaolong Chen*, Zhaoxiang Bian*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

1 Citation (Scopus)


Background and objectives: To review the efforts and progress in promoting quality and transparency of health research in China and to discuss how to improve.

Methods: We focused on three different types of health research: clinical trials, systematic reviews, and clinical practice guidelines, and summarized China's progress from their registration, implementation, and reporting stages.

Results: In the last 3 decades, China's major works include the following: 1) For registration, the trials and CPGs registries have been set up, and released policies to mandate registration and submission of protocols for trials. 2) For implementation, multiple clinical research and EBM centers have been established. The ResMan platform for data management has been created and required researchers to share results data. 3) For reporting, the Chinese EQUATOR Center has been set up. Translations and extensions of the CONSORT, PRISMA, and RIGHT have been published. 4) For traditional Chinese medicine (TCM), specific guidelines for the registration and reporting of TCM research have been developed.

Conclusion: China has made progress in promoting research quality and transparency, especially in research registration and reporting. Nevertheless, more can be done in data management and sharing for research implementation, and good publication practices in TCM.
Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalJournal of Clinical Epidemiology
Publication statusPublished - Dec 2022

User-Defined Keywords

  • Evidence-based medicine
  • Quality and transparency
  • Chinese EQUATOR centre
  • Registration
  • Data sharing
  • Reporting guideline


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