@article{4721651de5504204aa154a81d199e837,
title = "Preparation of 8-hydroxyquinoline derivatives as potential antibiotics against Staphylococcus aureus",
abstract = "This work describes the preparation of quinoline compounds as possible anti-bacterial agents. The synthesized quinoline derivatives show anti-bacterial activity towards Staphylococcus aureus. It is interesting to observe that the synthetic 5,7-dibromo-2-methylquinolin-8-ol (4) shows a similar minimum inhibitory concentration of 6.25 μg/mL as compared to that of methicillin (3.125 μg/mL) against Staphylococcus aureus.",
keywords = "Antibacterial agents, Antibiotics, Quinolines, Staphylococcus aureus",
author = "Lam, {Kim Hung} and Roberto Gambari and Lee, {Kenneth Ka Ho} and Chen, {Yi Xin} and Kok, {Stanton Hon Lung} and Wong, {Raymond Siu Ming} and Lau, {Fung Yi} and Cheng, {Chor Hing} and WONG, {Wai Yeung} and Zhaoxiang BIAN and Chan, {Albert Sun Chi} and Tang, {Johnny Cheuk On} and CHUI, {Chung Hin}",
note = "Funding Information: Dr. C.-H. Chui acknowledges the start-up research fund (38-40-116) from Hong Kong Baptist University. The authors also thank the financial support from Professor K.K.-H. Lee (Chinese University of Hong Kong), Professor X.-Z. Bian (03-16-176, Hong Kong Baptist University) and a research grant from Research Grant Committee, Innovation Technology Commission and Hong Kong Polytechnic University. Dr. J.C.-O. Tang acknowledges the internal grant from Hong Kong Polytechnic University (G-YM35) and Dr. P. Chan who provided the compounds for the biological experiments.",
year = "2014",
month = jan,
day = "1",
doi = "10.1016/j.bmcl.2013.10.072",
language = "English",
volume = "24",
pages = "367--370",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Ltd.",
number = "1",
}
