Abstract
Background: The most important advance of precision medicine (PM) has been a specific way to define and understand disease. However, PM may fail to be therapeutically effective if diseases are natural kinds.
Objective: To attest adverse consequences of treatments suggested by PM that do not generalize well.
Methods: Conceptual analysis of PM; Epistemology of clinical reasoning; Cases that show diseases as natural kinds to clash with epistemology of PM.
Results: Contemplation of future research options that could clarify the position of PM under the conception of diseases as natural kinds.
Conclusion: Need for improved design of future interventions that better acknowledge problematic epistemology of PM.
| Original language | English |
|---|---|
| Pages (from-to) | 835-842 |
| Number of pages | 8 |
| Journal | Journal of Evaluation in Clinical Practice |
| Volume | 28 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2022 |
User-Defined Keywords
- epistemology
- evolution
- inductive reasoning
- natural kinds
- precision medicine
