Practical synthetic approach to chiral sulfonimides (CSIs) - Chiral bronsted acids for organocatalysis

Hao He; Ling Yan Chen; Wai Yeung WONG; Wing Hong CHAN; Albert W M LEE

doi:10.1002/ejoc.201000477

Practical synthetic approach to chiral sulfonimides (CSIs) - Chiral bronsted acids for organocatalysis

Hao He, Ling Yan Chen, Wai Yeung WONG, Wing Hong CHAN, Albert W M LEE

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

48 Citations (Scopus)

Abstract

A general approach to the synthesis of optically pure 3,3'diaryl chiral sulfonimides (CSIs) from racemic BINOL has been developed. ortho-Lithiation is directed by the sulfonyl groups, and the resulting dihalides serve as the common precursors for the aryl-substituted CSIs.

Original language	English
Pages (from-to)	4181-4184
Number of pages	4
Journal	European Journal of Organic Chemistry
Issue number	22
DOIs	https://doi.org/10.1002/ejoc.201000477
Publication status	Published - Aug 2010

Scopus Subject Areas

Physical and Theoretical Chemistry
Organic Chemistry

User-Defined Keywords

Bransted acids
Chirality
Organocatalysis
Sulfonimides

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10.1002/ejoc.201000477

Cite this

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abstract = "A general approach to the synthesis of optically pure 3,3'diaryl chiral sulfonimides (CSIs) from racemic BINOL has been developed. ortho-Lithiation is directed by the sulfonyl groups, and the resulting dihalides serve as the common precursors for the aryl-substituted CSIs.",

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AU - He, Hao

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AU - WONG, Wai Yeung

AU - CHAN, Wing Hong

AU - LEE, Albert W M

PY - 2010/8

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AB - A general approach to the synthesis of optically pure 3,3'diaryl chiral sulfonimides (CSIs) from racemic BINOL has been developed. ortho-Lithiation is directed by the sulfonyl groups, and the resulting dihalides serve as the common precursors for the aryl-substituted CSIs.

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KW - Chirality

KW - Organocatalysis

KW - Sulfonimides

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DO - 10.1002/ejoc.201000477

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JO - European Journal of Organic Chemistry

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Practical synthetic approach to chiral sulfonimides (CSIs) - Chiral bronsted acids for organocatalysis

Abstract

Scopus Subject Areas

User-Defined Keywords

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