Poly[(9,9-dioctyl-fluorenyl-2,7-diyl)-co-fluorenone]-based orange fluorescence probe for cellular imaging

Yuan Liu, Hua Wang*, Peng Tao, Xing Liu, Yahong Liu, Qingchen Dong, Wenqing Liang, Qiang Zhao, Wai Yeung WONG, Bingshe Xu

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

3 Citations (Scopus)

Abstract

A novel orange fluorescence probe based on efficient fluorescence resonance energy transfer from poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-fluorenone] nanoparticles to Rhodamine B dye molecules was developed. This novel probe exhibited a larger Stokes shift, enhanced photostability and longer lifetime comparing to Rhodamine B dye molecules. Meanwhile, it demonstrated the characteristics that especially useful in live cell or in vivo studies, such as narrow full width at half-maximum emission, excitation bands in the visible range and the sensitivity of its fluorescence to temperature. Confocal fluorescence images of the fluorescent probe proved that it could effectively label HeLa cells.

Original languageEnglish
Pages (from-to)2287-2292
Number of pages6
JournalTetrahedron
Volume72
Issue number18
DOIs
Publication statusPublished - 5 May 2016

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

User-Defined Keywords

  • Cellular imaging
  • Orange fluorescence probe
  • Poly[(9,9-dioctyl-fluorenyl-2,7-diyl)-co-fluorenone]
  • Rhodamine B

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