Phytochemistry and Pharmacology of Carthamus tinctorius L.

Le Le Zhang, Ke Tian, Zheng Hai Tang, Xiao Jia Chen, Zhaoxiang BIAN, Yi Tao Wang, Jin Jian Lu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

121 Citations (Scopus)


Carthamus tinctorius L. is a multifunctional cash crop. Its flowers and seeds are extensively used in traditional herbal medicine in China, Korea, Japan, and other Asian countries, for treating various ailments such as gynecological, cardiovascular, and cerebrovascular diseases as well as blood stasis and osteoporosis. More than 100 compounds have been isolated and identified from C. tinctorius. Flavonoids and alkaloids, especially the quinochalcone c-glycoside hydroxysafflor yellow A, N-(p-Coumaroyl)serotonin, and N-feruloylserotonin, are responsible for most of the pharmacological activities of C. tinctorius. In this paper, comprehensive and up-to-date information on the phytochemistry and pharmacology of C. tinctorius is presented. This information will be helpful for further explorations of the therapeutic potential of C. tinctorius and may provide future research opportunities.

Original languageEnglish
Pages (from-to)197-226
Number of pages30
JournalThe American Journal of Chinese Medicine
Issue number2
Publication statusPublished - 1 Apr 2016

Scopus Subject Areas

  • Complementary and alternative medicine

User-Defined Keywords

  • Cardiovascular Protection
  • Carthamus tinctorius L.
  • Cerebrovascular Protection
  • Flavonoid, Hydroxysafflor Yellow A
  • Review


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