Phosphorescent Imaging of Living Cells Using a Cyclometalated Iridium(III) Complex

Edmond Dik Lung MA; Hai Jing Zhong; Wai Chung Fu; Daniel Shiu Hin Chan; Hiu Yee Kwan; David Wang Fun Fong; Lai Hon Chung; Chun Yuen Wong; Chung Hang Leung

doi:10.1371/journal.pone.0055751

Phosphorescent Imaging of Living Cells Using a Cyclometalated Iridium(III) Complex

Edmond Dik Lung MA^*, Hai Jing Zhong, Wai Chung Fu, Daniel Shiu Hin Chan, Hiu Yee Kwan, David Wang Fun Fong, Lai Hon Chung, Chun Yuen Wong, Chung Hang Leung

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

34 Citations (Scopus)

Abstract

A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)₂(H₂O]₂)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.

Original language	English
Article number	e55751
Number of pages	8
Journal	PLoS ONE
Volume	8
Issue number	2
DOIs	https://doi.org/10.1371/journal.pone.0055751
Publication status	Published - 14 Feb 2013

Scopus Subject Areas

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)
General

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title = "Phosphorescent Imaging of Living Cells Using a Cyclometalated Iridium(III) Complex",

abstract = "A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)2(H2O]2)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.",

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AU - MA, Edmond Dik Lung

AU - Zhong, Hai Jing

AU - Fu, Wai Chung

AU - Chan, Daniel Shiu Hin

AU - Kwan, Hiu Yee

AU - Fong, David Wang Fun

AU - Chung, Lai Hon

AU - Wong, Chun Yuen

AU - Leung, Chung Hang

PY - 2013/2/14

Y1 - 2013/2/14

N2 - A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)2(H2O]2)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.

AB - A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)2(H2O]2)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.

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JO - PLoS ONE

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Phosphorescent Imaging of Living Cells Using a Cyclometalated Iridium(III) Complex

Abstract

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