Perception of brassinosteroids by the extracellular domain of the receptor kinase BRI1

Zuhua He, Zhi-Yong Wang, Jianming Li, Qun Zhu, Chris Lamb, Pamela Ronald, Joanne Chory*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

367 Citations (Scopus)

Abstract

An assay was developed to study plant receptor kinase activation and signaling mechanisms. The extracellular leucine-rich repeat (LRR) and transmembrane domains of the Arabidopsis receptor kinase BRI1, which is implicated in brassinosteroid signaling, were fused to the serine/threonine kinase domain of XA21, the rice disease resistance receptor. The chimeric receptor initiates plant defense responses in rice cells upon treatment with brassinosteroids. These results, which indicate that the extracellular domain of BRI1 perceives brassinosteroids, suggest a general signaling mechanism for the LRR receptor kinases of plants. This system should allow the discovery of ligands for the LRR kinases, the largest group of plant receptor kinases.

Original languageEnglish
Pages (from-to)2360-2363
Number of pages4
JournalScience
Volume288
Issue number5475
DOIs
Publication statusPublished - 30 Jun 2000

Scopus Subject Areas

  • General

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