Pd-Catalyzed sequential B(3)–I/B(4)–H bond activation for the synthesis of 3,4-benzo-o-carboranes

  • Yixiu Ge
  • , Jie Zhang
  • , Zaozao Qiu*
  • , Zuowei Xie*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

9 Citations (Scopus)

Abstract

A palladium-catalyzed sequential B(3)–I and B(4)–H bond activation has been achieved for the synthesis of 3,4-benzo-o-carboranes via a formal [2 + 2 + 2] cycloaddition of 3-I-o-carborane with 2 equiv. of arylalkynes. This represents a new protocol to construct o-carborane-fused cyclics in one process, in which the Pd fragment migrates formally from the B(3) to B(4) position of the cage.

Original languageEnglish
Pages (from-to)1766-1773
Number of pages8
JournalDalton Transactions
Volume50
Issue number5
Early online date24 Dec 2020
DOIs
Publication statusPublished - 7 Feb 2021

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