Abstract
A chiral palladium/copper (Pd/Cu) co-catalytic system which could enable asymmetric ring opening reaction of azabenzonorbornadienes with terminal alkynes is reported. This system comprises palladium(II) acetate [Pd(OAc)2]/(R)-xyl-Binap and copper(I) triflate (CuOTf). A good substrate scope was found, with excellent enantioselective outcomes (up to >99.9 % ee). A reaction mechanism involving two metal complexes is also proposed.
Original language | English |
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Pages (from-to) | 2827-2832 |
Number of pages | 6 |
Journal | Advanced Synthesis & Catalysis |
Volume | 355 |
Issue number | 14-15 |
DOIs | |
Publication status | Published - 11 Oct 2013 |