Palladium-catalyzed Suzuki-Miyaura coupling with aryl and heteroaryl bromides using N,N,N',N'-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine

Kun Wang; Tao YI; Xiaojun Yu; Xueli Zheng; Haiyan Fu; Hua Chen; Ruixiang Li

doi:10.1002/aoc.2869

Palladium-catalyzed Suzuki-Miyaura coupling with aryl and heteroaryl bromides using N,N,N',N'-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine

Kun Wang
, Tao YI
, Xiaojun Yu
, Xueli Zheng
, Haiyan Fu
, Hua Chen
, Ruixiang Li^*

^*Corresponding author for this work

School of Chinese Medicine

Research output: Contribution to journal › Journal article › peer-review

17 Citations (Scopus)

Abstract

An easily prepared tetraphosphine N,N,N',N'-tetra(diphenylphosphinomethyl)- 1,2-ethylenediamine (1) combined with PdCl ₂ affords an efficient catalytic system for Suzuki cross-coupling of aryl and heteroaryl bromides. A high turnover number of 750 000 is obtained with the catalyst loading as low as 1 ppm. This catalyst system exhibits good stability and longevity. In this study, a broad scope of substrates is investigated and satisfactory yields are obtained.

Original language	English
Pages (from-to)	342-346
Number of pages	5
Journal	Applied Organometallic Chemistry
Volume	26
Issue number	7
DOIs	https://doi.org/10.1002/aoc.2869
Publication status	Published - Jul 2012

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palladium
Suzuki-Miyaura coupling
tetraphosphine

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10.1002/aoc.2869

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title = "Palladium-catalyzed Suzuki-Miyaura coupling with aryl and heteroaryl bromides using N,N,N',N'-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine",

abstract = "An easily prepared tetraphosphine N,N,N',N'-tetra(diphenylphosphinomethyl)- 1,2-ethylenediamine (1) combined with PdCl 2 affords an efficient catalytic system for Suzuki cross-coupling of aryl and heteroaryl bromides. A high turnover number of 750 000 is obtained with the catalyst loading as low as 1 ppm. This catalyst system exhibits good stability and longevity. In this study, a broad scope of substrates is investigated and satisfactory yields are obtained.",

keywords = "palladium, Suzuki-Miyaura coupling, tetraphosphine",

author = "Kun Wang and Tao YI and Xiaojun Yu and Xueli Zheng and Haiyan Fu and Hua Chen and Ruixiang Li",

year = "2012",

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doi = "10.1002/aoc.2869",

language = "English",

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pages = "342--346",

journal = "Applied Organometallic Chemistry",

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T1 - Palladium-catalyzed Suzuki-Miyaura coupling with aryl and heteroaryl bromides using N,N,N',N'-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine

AU - Wang, Kun

AU - YI, Tao

AU - Yu, Xiaojun

AU - Zheng, Xueli

AU - Fu, Haiyan

AU - Chen, Hua

AU - Li, Ruixiang

PY - 2012/7

Y1 - 2012/7

N2 - An easily prepared tetraphosphine N,N,N',N'-tetra(diphenylphosphinomethyl)- 1,2-ethylenediamine (1) combined with PdCl 2 affords an efficient catalytic system for Suzuki cross-coupling of aryl and heteroaryl bromides. A high turnover number of 750 000 is obtained with the catalyst loading as low as 1 ppm. This catalyst system exhibits good stability and longevity. In this study, a broad scope of substrates is investigated and satisfactory yields are obtained.

AB - An easily prepared tetraphosphine N,N,N',N'-tetra(diphenylphosphinomethyl)- 1,2-ethylenediamine (1) combined with PdCl 2 affords an efficient catalytic system for Suzuki cross-coupling of aryl and heteroaryl bromides. A high turnover number of 750 000 is obtained with the catalyst loading as low as 1 ppm. This catalyst system exhibits good stability and longevity. In this study, a broad scope of substrates is investigated and satisfactory yields are obtained.

KW - palladium

KW - Suzuki-Miyaura coupling

KW - tetraphosphine

UR - https://www.scopus.com/pages/publications/84862882538

U2 - 10.1002/aoc.2869

DO - 10.1002/aoc.2869

M3 - Journal article

AN - SCOPUS:84862882538

SN - 0268-2605

VL - 26

SP - 342

EP - 346

JO - Applied Organometallic Chemistry

JF - Applied Organometallic Chemistry

IS - 7

ER -

Palladium-catalyzed Suzuki-Miyaura coupling with aryl and heteroaryl bromides using N,N,N',N'-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine

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