Palladium-catalyzed borylation of aryl (pseudo)halides and its applications in biaryl synthesis

Hong Ji*, Jianghong Cai, Nana Gan, Zhaohua Wang, Liyang Wu, Guorong Li, Tao Yi

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

5 Citations (Scopus)
57 Downloads (Pure)


A facile and efficient palladium-catalyzed borylation of aryl (pseudo)halides at room temperature has been developed. Arylboronic esters were expeditiously assembled in good yields and with a broad substrate scope and good functional group compatibility. This approach has been successfully applied to the one-pot two-step borylation/Suzuki-Miyaura cross-coupling reaction, providing a concise access to biaryl compounds from readily available aryl halides. Furthermore, a parallel synthesis of biaryl analogs is accomplished at room temperature using the strategy, which enhances the practical usefulness of this method.

Original languageEnglish
Article number136
Number of pages8
JournalChemistry Central Journal
Publication statusPublished - 19 Dec 2018

Scopus Subject Areas

  • Chemistry(all)

User-Defined Keywords

  • Aryl (pseudo)halides
  • Biaryl synthesis
  • Palladium-catalyzed borylation
  • Suzuki-Miyaura cross coupling


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