Abstract
A palladium/(R)-Binap catalyst for asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed that afforded the corresponding substituted dihydronaphthalenes in good yields (up to 97%) with excellent enantioselectivities (up to >99% ee). To the best of our knowledge, this represents the first palladium-catalyzed asymmetric ring opening reaction of azabenzonorbornadienes with heteronucleophiles.
| Original language | English |
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| Pages (from-to) | 3121-3125 |
| Number of pages | 5 |
| Journal | Advanced Synthesis & Catalysis |
| Volume | 357 |
| Issue number | 14-15 |
| DOIs | |
| Publication status | Published - 2015 |