Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic Amines

Zhiwu Lu; Jun Wang; Baiqiu Han; Sifeng Li; Yongyun Zhou; Baomin Fan

doi:10.1002/adsc.201500530

Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic Amines

Zhiwu Lu, Jun Wang^*, Baiqiu Han, Sifeng Li, Yongyun Zhou, Baomin Fan^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

40 Citations (Scopus)

Abstract

A palladium/(R)-Binap catalyst for asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed that afforded the corresponding substituted dihydronaphthalenes in good yields (up to 97%) with excellent enantioselectivities (up to >99% ee). To the best of our knowledge, this represents the first palladium-catalyzed asymmetric ring opening reaction of azabenzonorbornadienes with heteronucleophiles.

Original language	English
Pages (from-to)	3121-3125
Number of pages	5
Journal	Advanced Synthesis & Catalysis
Volume	357
Issue number	14-15
DOIs	https://doi.org/10.1002/adsc.201500530
Publication status	Published - 2015

Access to Document

10.1002/adsc.201500530

Cite this

@article{edc81a78627b4c40ab376ddbeb6826d8,

title = "Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic Amines",

abstract = "A palladium/(R)-Binap catalyst for asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed that afforded the corresponding substituted dihydronaphthalenes in good yields (up to 97%) with excellent enantioselectivities (up to >99% ee). To the best of our knowledge, this represents the first palladium-catalyzed asymmetric ring opening reaction of azabenzonorbornadienes with heteronucleophiles.",

author = "Zhiwu Lu and Jun Wang and Baiqiu Han and Sifeng Li and Yongyun Zhou and Baomin Fan",

year = "2015",

doi = "10.1002/adsc.201500530",

language = "English",

volume = "357",

pages = "3121--3125",

journal = "Advanced Synthesis & Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH Verlag",

number = "14-15",

}

TY - JOUR

T1 - Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic Amines

AU - Lu, Zhiwu

AU - Wang, Jun

AU - Han, Baiqiu

AU - Li, Sifeng

AU - Zhou, Yongyun

AU - Fan, Baomin

PY - 2015

Y1 - 2015

N2 - A palladium/(R)-Binap catalyst for asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed that afforded the corresponding substituted dihydronaphthalenes in good yields (up to 97%) with excellent enantioselectivities (up to >99% ee). To the best of our knowledge, this represents the first palladium-catalyzed asymmetric ring opening reaction of azabenzonorbornadienes with heteronucleophiles.

AB - A palladium/(R)-Binap catalyst for asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed that afforded the corresponding substituted dihydronaphthalenes in good yields (up to 97%) with excellent enantioselectivities (up to >99% ee). To the best of our knowledge, this represents the first palladium-catalyzed asymmetric ring opening reaction of azabenzonorbornadienes with heteronucleophiles.

U2 - 10.1002/adsc.201500530

DO - 10.1002/adsc.201500530

M3 - Journal article

SN - 1615-4150

VL - 357

SP - 3121

EP - 3125

JO - Advanced Synthesis & Catalysis

JF - Advanced Synthesis & Catalysis

IS - 14-15

ER -

Palladium-Catalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic Amines

Abstract

Access to Document

Fingerprint

Cite this