Osmium(vi) complexes as a new class of potential anti-cancer agents

Wen Xiu Ni, Wai Lun Man, Myra Ting Wai Cheung, Raymond Wai Yin Sun, Yuan Lan Shu, Yun Wah Lam*, Chi Ming Che*, Tai Chu Lau*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

A nitridoosmium(vi) complex [OsVI(N)(sap)(OH2)Cl] (H2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate.

Original languageEnglish
Pages (from-to)2140-2142
Number of pages3
JournalChemical Communications
Volume47
Issue number7
Early online date4 Jan 2011
DOIs
Publication statusPublished - 21 Feb 2011

Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Osmium(vi) complexes as a new class of potential anti-cancer agents'. Together they form a unique fingerprint.

Cite this