Optical voltage imaging in neurons: moving from technology development to practical tool

Thomas Knöpfel; Chenchen Song

doi:10.1038/s41583-019-0231-4

Optical voltage imaging in neurons: moving from technology development to practical tool

Thomas Knöpfel^*, Chenchen Song

^*Corresponding author for this work

Department of Physics

Research output: Contribution to journal › Journal article › peer-review

140 Citations (Scopus)

Abstract

A central goal in neuroscience is to determine how the brain’s neuronal circuits generate perception, cognition and emotions and how these lead to appropriate behavioural actions. A methodological platform based on genetically encoded voltage indicators (GEVIs) that enables the monitoring of large-scale circuit dynamics has brought us closer to this ambitious goal. This Review provides an update on the current state of the art and the prospects of emerging optical GEVI imaging technologies.

Original language	English
Pages (from-to)	719-727
Number of pages	9
Journal	Nature Reviews Neuroscience
Volume	20
Issue number	12
Early online date	8 Nov 2019
DOIs	https://doi.org/10.1038/s41583-019-0231-4
Publication status	Published - Dec 2020

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10.1038/s41583-019-0231-4

Cite this

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Optical voltage imaging in neurons: moving from technology development to practical tool

Abstract

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