Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex

Ga Lai Law; Cornelia Man; David Parker; James W. Walton

doi:10.1039/b924679g

Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex

Ga Lai Law
, Cornelia Man
, David Parker^*
, James W. Walton

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

51 Citations (Scopus)

Abstract

The emission intensity of a monocationic Tb or Eu(iii) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.

Original language	English
Pages (from-to)	2391-2393
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	14
Early online date	2 Feb 2010
DOIs	https://doi.org/10.1039/b924679g
Publication status	Published - 14 Apr 2010

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10.1039/b924679g

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title = "Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex",

abstract = "The emission intensity of a monocationic Tb or Eu(iii) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.",

author = "Law, \{Ga Lai\} and Cornelia Man and David Parker and Walton, \{James W.\}",

note = "We thank EPSRC and CISbio s.a. for support. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2010",

year = "2010",

month = apr,

day = "14",

doi = "10.1039/b924679g",

language = "English",

volume = "46",

pages = "2391--2393",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex

AU - Law, Ga Lai

AU - Man, Cornelia

AU - Parker, David

AU - Walton, James W.

N1 - We thank EPSRC and CISbio s.a. for support. Publisher Copyright: © The Royal Society of Chemistry 2010

PY - 2010/4/14

Y1 - 2010/4/14

N2 - The emission intensity of a monocationic Tb or Eu(iii) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.

AB - The emission intensity of a monocationic Tb or Eu(iii) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.

UR - https://www.scopus.com/pages/publications/77949779534

UR - https://pubs.rsc.org/en/content/articlelanding/2010/cc/b924679g

U2 - 10.1039/b924679g

DO - 10.1039/b924679g

M3 - Journal article

C2 - 20309461

AN - SCOPUS:77949779534

SN - 1359-7345

VL - 46

SP - 2391

EP - 2393

JO - Chemical Communications

JF - Chemical Communications

IS - 14

ER -

Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(iii) complex

Abstract

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