Novel ardisiphenol D derivatives 1279P1 and 1279P2: promising anti-colorectal cancer agents targeting the PI3K/Akt pathway and lipogenesis enzymes

Bai-Sen Chen; Wai-I Chik; Hong-Jie Zhang

doi:10.1016/j.phytol.2025.103899

Novel ardisiphenol D derivatives 1279P1 and 1279P2: promising anti-colorectal cancer agents targeting the PI3K/Akt pathway and lipogenesis enzymes

Bai-Sen Chen^*
, Wai-I Chik
, Hong-Jie Zhang

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Journal article › peer-review

Original language	English
Article number	103899
Journal	Phytochemistry Letters
Volume	69
Issue number	Supplement
DOIs	https://doi.org/10.1016/j.phytol.2025.103899
Publication status	Published - Oct 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

User-Defined Keywords

Ardisiphenol D derivatives
PI3K/AKT pathway
de novo lipogenesis
anti-colorectal cancer

Access to Document

10.1016/j.phytol.2025.103899

Cite this

@article{14c7bfb275484fa683ba57fa58b00017,

title = "Novel ardisiphenol D derivatives 1279P1 and 1279P2: promising anti-colorectal cancer agents targeting the PI3K/Akt pathway and lipogenesis enzymes",

keywords = "Ardisiphenol D derivatives, PI3K/AKT pathway, de novo lipogenesis, anti-colorectal cancer",

author = "Bai-Sen Chen and Wai-I Chik and Hong-Jie Zhang",

note = "Publisher Copyright: {\textcopyright} 2025 Elsevier B.V.",

year = "2025",

month = oct,

doi = "10.1016/j.phytol.2025.103899",

language = "English",

volume = "69",

journal = "Phytochemistry Letters",

issn = "1874-3900",

publisher = "Elsevier Ltd.",

number = "Supplement",

}

TY - JOUR

T1 - Novel ardisiphenol D derivatives 1279P1 and 1279P2: promising anti-colorectal cancer agents targeting the PI3K/Akt pathway and lipogenesis enzymes

AU - Chen, Bai-Sen

AU - Chik, Wai-I

AU - Zhang, Hong-Jie

PY - 2025/10

Y1 - 2025/10

KW - Ardisiphenol D derivatives

KW - PI3K/AKT pathway

KW - de novo lipogenesis

KW - anti-colorectal cancer

U2 - 10.1016/j.phytol.2025.103899

DO - 10.1016/j.phytol.2025.103899

M3 - Journal article

SN - 1874-3900

VL - 69

JO - Phytochemistry Letters

JF - Phytochemistry Letters

IS - Supplement

M1 - 103899

ER -