TY - JOUR
T1 - NMR and Luminescence Binding Studies of Ytterbium, Thulium, and Europium Macrocyclic Complexes with Phosphorus(V) Oxy Anions
AU - Atkinson, Paul
AU - Bretonnière, Yann
AU - Parker, David
AU - Muller, Gilles
N1 - We thank EPSRC and ONE-NE for support and Professor Andre Merbach for his creative genius in unraveling mechanistic details of solution reaction dynamics, especially involving d- and f-block ions and their coordination complexes.
Publisher copyright:
© 2005 Verlag Helvetica Chimica Acta AG, Zürich, Switzerland
PY - 2005/3
Y1 - 2005/3
N2 - The binding of a series of phosphate anions to coordinatively unsaturated macrocyclic complexes of Yb, Tm, and Eu was studied by 1H-NMR, emission and circularly polarized luminescence (CPL) spectroscopy. Each ternary adduct was distinguished by its spectral profile. With O-phosphorylated amino acids and peptides, chemoselective ligation of the phosphate moiety was favored by Eu over chelation involving the terminal amino group, which was competitive for Tm and Yb. A preference for binding O-phosphono-L-tyrosine sites was found with various Eu complexes, and was signalled by ratiometric changes in metal-based emission and CPL spectra.
AB - The binding of a series of phosphate anions to coordinatively unsaturated macrocyclic complexes of Yb, Tm, and Eu was studied by 1H-NMR, emission and circularly polarized luminescence (CPL) spectroscopy. Each ternary adduct was distinguished by its spectral profile. With O-phosphorylated amino acids and peptides, chemoselective ligation of the phosphate moiety was favored by Eu over chelation involving the terminal amino group, which was competitive for Tm and Yb. A preference for binding O-phosphono-L-tyrosine sites was found with various Eu complexes, and was signalled by ratiometric changes in metal-based emission and CPL spectra.
UR - https://www.scopus.com/pages/publications/16444385626
U2 - 10.1002/hlca.200590025
DO - 10.1002/hlca.200590025
M3 - Journal article
AN - SCOPUS:16444385626
SN - 0018-019X
VL - 88
SP - 391
EP - 405
JO - Helvetica Chimica Acta
JF - Helvetica Chimica Acta
IS - 3
ER -
