Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air

Fei Fei Wu; Ji Ning Zhou; Qiang Fang; Yi Hu Hu; Shijun Li; Xi Chang Zhang; Albert S.C. Chan; Jing Wu

doi:10.1002/asia.201200512

Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air

Fei Fei Wu
, Ji Ning Zhou
, Qiang Fang
, Yi Hu Hu
, Shijun Li
, Xi Chang Zhang
, Albert S.C. Chan
, Jing Wu^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

28 Citations (Scopus)

Abstract

Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH ₃, formed an effective catalyst system for the Ni ^II-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90 % ee. The practical potential of the protocol was evinced by its good air-stability.

Original language	English
Pages (from-to)	2527-2530
Number of pages	4
Journal	Chemistry - An Asian Journal
Volume	7
Issue number	11
DOIs	https://doi.org/10.1002/asia.201200512
Publication status	Published - Nov 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

User-Defined Keywords

asymmetric catalysis
hydrosilylation
ketones
nickel
P ligands

Access to Document

10.1002/asia.201200512

Cite this

@article{46913aa7501b4b25a95df008d3c99f78,

title = "Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air",

abstract = "Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH 3, formed an effective catalyst system for the Ni II-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90 \% ee. The practical potential of the protocol was evinced by its good air-stability.",

keywords = "asymmetric catalysis, hydrosilylation, ketones, nickel, P ligands",

author = "Wu, \{Fei Fei\} and Zhou, \{Ji Ning\} and Qiang Fang and Hu, \{Yi Hu\} and Shijun Li and Zhang, \{Xi Chang\} and Chan, \{Albert S.C.\} and Jing Wu",

note = "National Natural Science Foundation of China. Grant Numbers: 21172049, 21032003, 91127010, 21072039 Public Welfare Technology and Application Program of Zhejiang Province. Grant Number: 2010C31042 Special Funds for Key Innovation Team of Zhejiang Province. Grant Number: 2010R50017 Publisher copyright: {\textcopyright} 2012 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2012",

month = nov,

doi = "10.1002/asia.201200512",

language = "English",

volume = "7",

pages = "2527--2530",

journal = "Chemistry - An Asian Journal",

issn = "1861-4728",

publisher = "John Wiley \& Sons Ltd",

number = "11",

}

TY - JOUR

T1 - Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air

AU - Wu, Fei Fei

AU - Zhou, Ji Ning

AU - Fang, Qiang

AU - Hu, Yi Hu

AU - Li, Shijun

AU - Zhang, Xi Chang

AU - Chan, Albert S.C.

AU - Wu, Jing

N1 - National Natural Science Foundation of China. Grant Numbers: 21172049, 21032003, 91127010, 21072039 Public Welfare Technology and Application Program of Zhejiang Province. Grant Number: 2010C31042 Special Funds for Key Innovation Team of Zhejiang Province. Grant Number: 2010R50017 Publisher copyright: © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

PY - 2012/11

Y1 - 2012/11

N2 - Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH 3, formed an effective catalyst system for the Ni II-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90 % ee. The practical potential of the protocol was evinced by its good air-stability.

AB - Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH 3, formed an effective catalyst system for the Ni II-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90 % ee. The practical potential of the protocol was evinced by its good air-stability.

KW - asymmetric catalysis

KW - hydrosilylation

KW - ketones

KW - nickel

KW - P ligands

UR - https://www.scopus.com/pages/publications/84867468096

U2 - 10.1002/asia.201200512

DO - 10.1002/asia.201200512

M3 - Journal article

C2 - 22927322

AN - SCOPUS:84867468096

SN - 1861-4728

VL - 7

SP - 2527

EP - 2530

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 11

ER -

Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air

Abstract

UN SDGs

User-Defined Keywords

Access to Document

Other files and links

Fingerprint

Cite this