Nickel(II)-Dipyridylphosphine-Catalyzed Enantioselective Hydrosilylation of Ketones in Air

Fei Fei Wu, Ji Ning Zhou, Qiang Fang, Yi Hu Hu, Shijun Li, Xi Chang Zhang, Albert S.C. Chan, Jing Wu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

27 Citations (Scopus)

Abstract

Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH 3, formed an effective catalyst system for the Ni II-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90 % ee. The practical potential of the protocol was evinced by its good air-stability.

Original languageEnglish
Pages (from-to)2527-2530
Number of pages4
JournalChemistry - An Asian Journal
Volume7
Issue number11
DOIs
Publication statusPublished - Nov 2012

User-Defined Keywords

  • asymmetric catalysis
  • hydrosilylation
  • ketones
  • nickel
  • P ligands

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