New triterpene diglycosides from the rhizome of Cimifuga foetida

Lirong Sun, Jian Yan, Yin Nian, Lin Zhou, Hongjie Zhang, Minghua Qiu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

14 Citations (Scopus)


Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and α-D-glucopyranosyl-l-β-D- fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida. The new triterpene diglycosides 1-5 were identified as cimiacerol-3-O-β-D- xylopyranosyl-(1″→3′)-β-D-xylopyranoside, 12β-hydroxycimigenol-3-O-β-D-xylopyranosyl-(1″→3′) -β-D-xylopyranoside, 25-O-acetylcimig- enol-3-O-β-D-xylopyranosyl- (1″→3′)-β-D-xylopyranoside, 24-acetylhydroshengmanol-3-O- β-D-xylopyranosyl-(1″→3′)-β-D-xylopyranoside and 26-deoxyacetylacteol-3-O-β-D-xylo- pyranosyl-(1″→3′)- β-D-xylopyranoside, respectively, based on analysis of their spectral data and chemical reactions.

Original languageEnglish
Pages (from-to)1712-1721
Number of pages10
Issue number8
Publication statusPublished - Aug 2008

Scopus Subject Areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

User-Defined Keywords

  • Cimicifuga foetida
  • Cimifosides
  • Cycloartane triterpenoid
  • Diglycosides


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