Neurotrophin receptor immunostaining in the vestibular nuclei of rats

F. X. Zhang, C. H. Lai, S. K. Lai, Kin Lam YUNG, D. K.Y. Shum, Y. S. Chan*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

15 Citations (Scopus)

Abstract

The distribution of high-affinity neurotrophin receptors in cells of the vestibular nuclear complex and its subnuclei of adult rats was examined. We noted a high density of tyrosine kinase (Trk) A- and B- and a lower density of TrkC-immunostained cells. In particular, long, intensely labelled immunostained-TrkB fibres formed networks in the neuropil. BothTrkA- and TrkB-immunostained cells were widely distributed in the lateral, medial and spinal vestibular nuclei, and were less frequently seen in the superior vestibular nucleus, x and y subnuclei. However, immunostaining for TrkC was weak in many cells within the vestibular nuclei. The widespread and abundant neuronal distribution of Trk receptors predicts that their associated neurotrophins exert significant effects on individual cells within the vestibular nuclei.

Original languageEnglish
Pages (from-to)851-855
Number of pages5
JournalNeuroReport
Volume14
Issue number6
DOIs
Publication statusPublished - 6 May 2003

Scopus Subject Areas

  • Neuroscience(all)

User-Defined Keywords

  • Tyrosine kinase receptors
  • Vestibular nucleus

Fingerprint

Dive into the research topics of 'Neurotrophin receptor immunostaining in the vestibular nuclei of rats'. Together they form a unique fingerprint.

Cite this